Search results for "induced [background]"

showing 10 items of 366 documents

Activation-Induced Rigidity in Neurologically and Cognitively Healthy Individuals Aged 18-90 Years: A Cross-Sectional Study.

2021

Background: Rigidity is a key clinical feature of Parkinson’s disease (PD), but in a very early phase of the disease it may be absent and can be enhanced through active movements of the arm contralateral to the one being tested. Objective: To evaluate in a large cohort of neurologically and cognitively healthy (NCH) subjects aged 18–90 years if activation-induced rigidity (AR) is present in all age classes, and if there are biological differences between subjects showing AR (AR+) and not showing AR (AR-). Methods: 2,228 NCH subjects categorized as young adult (18–44 years), adult (45–64 years), elderly (65–74 years), and old/oldest-old (75–90 years) were included in the analysis, and underw…

Adultmedicine.medical_specialtyParkinson's diseaseAdolescentCross-sectional studyAudiologylacunesProdromal phaseYoung AdultCellular and Molecular NeuroscienceLateral ventriclesCognitionAtrophyHumansMedicinehealthy aging subjectscaudate atrophyYoung adultAgedglobal cerebral atrophyAged 80 and overActivation-induced rigiditybusiness.industryBrainParkinson DiseaseMiddle Agedwhite matter hyperintensitiesmedicine.diseaseMagnetic Resonance ImagingHyperintensityCross-Sectional StudiesHealthy individualsSettore MED/26 - NeurologiaNeurology (clinical)Atrophybusiness
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Induction of Mitochondrial Changes Associated with Oxidative Stress on Very Long Chain Fatty Acids (C22:0, C24:0, or C26:0)-Treated Human Neuronal Ce…

2012

In Alzheimer's disease, lipid alterations point towards peroxisomal dysfunctions. Indeed, a cortical accumulation of saturated very long chain fatty acids (VLCFAs: C22:0, C24:0, C26:0), substrates for peroxisomalβ-oxidation, has been found in Alzheimer patients. This study was realized to investigate the effects of VLCFAs at the mitochondrial level since mitochondrial dysfunctions play crucial roles in neurodegeneration. On human neuronal SK-NB-E cells treated with C22:0, C24:0, or C26:0 (0.1–20 μM; 48 h), an inhibition of cell growth and mitochondrial dysfunctions were observed by cell counting with trypan blue, MTT assay, and measurement of mitochondrial transmembrane potential (Δψm) with…

AgingArticle SubjectMitochondrionBiologymedicine.disease_causeBiochemistryMitochondrial apoptosis-induced channelchemistry.chemical_compoundSuperoxidesCell Line TumormedicineHumanslcsh:QH573-671Cell ShapeCell ProliferationMembrane Potential MitochondrialNeuronslcsh:CytologySuperoxideFatty AcidsNeurodegenerationCell BiologyGeneral MedicinePeroxisomeFlow Cytometrymedicine.diseaseMolecular biologyMitochondriaCell biologyOxidative StressProtein SubunitsMicroscopy FluorescencechemistryMultiprotein ComplexesDNAJA3ATP–ADP translocaseOxidative stressResearch ArticleOxidative Medicine and Cellular Longevity
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Systemic administration of D-penicillamine prevents the locomotor activation after intra-VTA ethanol administration in rats.

2010

Although recently published studies seem to confirm the important role displayed by acetaldehyde (ACH), the main metabolite of ethanol, in the behavioral effects of ethanol, the origin of ACH is still a matter of debate. While some authors confer more importance to the central (brain metabolism) origin of ACH, others indicate that the hepatic origin could be more relevant. In this study we have addressed this topic using an experimental approach that combines local microinjections of ethanol into the ventral tegmental area (VTA) (which guarantees the brain origin of the ACH) to induce motor activation in rats together with systemic administration (i.p.) of several doses (0, 12.5, 25 and 50 …

AgonistLocomotor activityMalemedicine.drug_classMetaboliteCentral nervous systemAcetaldehydePharmacologyMotor Activitychemistry.chemical_compoundAlcohol-Induced Disorders Nervous SystemmedicineAnimalsRats WistarReceptorEthanolGeneral NeurosciencePenicillamineD-PenicillaminePenicillamineVentral Tegmental AreaCentral Nervous System DepressantsRatsVentral tegmental areaDAMGOBrain metabolism of ethanolDisease Models Animalmedicine.anatomical_structurechemistryBiochemistrySystemic administrationVTAmedicine.drugNeuroscience letters
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Characters, bilinear forms and solvable groups

2016

Abstract We prove a number of results about the ordinary and Brauer characters of finite solvable groups in characteristic 2, by defining and using the concept of the extended nucleus of a real irreducible character. In particular we show that the Isaacs canonical lift of a real irreducible Brauer character has Frobenius–Schur indicator +1. We also show that the principal indecomposable module corresponding to a real irreducible Brauer character affords a quadratic geometry if and only if each extended nucleus is a split extension of a nucleus.

Algebra and Number TheoryBrauer's theorem on induced charactersMathematics::Rings and Algebras010102 general mathematicsBilinear form01 natural sciencesCombinatoricsLift (mathematics)Frobenius–Schur indicatorQuadratic equationSolvable group0103 physical sciences010307 mathematical physics0101 mathematicsMathematics::Representation TheoryIndecomposable moduleMathematicsJournal of Algebra
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On the representation theory of quantum Heisenberg group and algebra

1994

We show that the quantum Heisenberg groupH q (1) and its *-Hopf algebra structure can be obtained by means of contraction from quantumSU q (2) group. Its dual Hopf algebra is the quantum Heisenberg algebraU q (h(1)). We derive left and right regular representations forU q (h(1)) as acting on its dualH q (1). Imposing conditions on the right representation, the left representation is reduced to an irreducible holomorphic representation with an associated quantum coherent state. Realized in the Bargmann-Hilbert space of analytic functions the unitarity of regular representation is also shown. By duality, left and right regular representations for quantum Heisenberg group with the quantum Heis…

AlgebraInduced representationQuantum groupTheta representationRestricted representationTrivial representationRegular representationHeisenberg groupGeneral Physics and AstronomyRepresentation theory of finite groupsMathematicsCzechoslovak Journal of Physics
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Characters and Blocks of Finite Groups

1998

This is a clear, accessible and up-to-date exposition of modular representation theory of finite groups from a character-theoretic viewpoint. After a short review of the necessary background material, the early chapters introduce Brauer characters and blocks and develop their basic properties. The next three chapters study and prove Brauer's first, second and third main theorems in turn. These results are then applied to prove a major application of finite groups, the Glauberman Z*-theorem. Later chapters examine Brauer characters in more detail. The relationship between blocks and normal subgroups is also explored and the modular characters and blocks in p-solvable groups are discussed. Fi…

AlgebraNormal subgroupPure mathematicsModular representation theoryBrauer's theorem on induced charactersSylow theoremsCharacter theoryOrder (group theory)Classification of finite simple groupsRepresentation theory of finite groupsMathematics
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Large orbits ofp-groups on characters and applications to character degrees

2005

We prove that if ap-groupA acts on a solvablep′-groupG then there is a “large” orbit on the ordinary complex irreducible characters ofG. As a consequence of this theorem we obtain results that relate ordinary and Brauer character degrees.

AlgebraPure mathematicsBrauer's theorem on induced charactersCharacter (mathematics)General MathematicsAlgebra over a fieldOrbit (control theory)Mathematics::Representation TheoryMathematicsIsrael Journal of Mathematics
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Asthma, allergies and respiratory symptoms in different activity groups of swimmers exercising in swimming halls

2021

Abstract Background Respiratory symptoms are common in competitive swimmers. However, among these and in swimmers at other activity levels the swimming distance, the total spent time in swimming halls and their medical background varies. Our objectives were, first, to assess their medical histories and the associations with respiratory symptoms among swimmers in different activity groups and then second, to study the pulmonary function findings and related medications in competitive swimmers who exercise in swimming hall environments the most. Methods First, 1118 participants consisting of 133 competitive-, 734 fitness- and 251 occasional swimmers answered questionnaires concerning their me…

AllergySports medicineAllergyCHILDRENallergiaPulmonary function testingRESPONSIVENESS0302 clinical medicineastmaOrthopedics and Sports MedicineRespiratory symptomsRespiratory systemswimmingSwimming hallsmedicine.diagnostic_testRehabilitationpulmonary functionrespiratory symptomsuimahallitLUNG-FUNCTIONhengityselinten tauditHEALTHRC1200-1245Spirometrymedicine.medical_specialtyPulmonary functionPhysical Therapy Sports Therapy and RehabilitationSpirometry testing03 medical and health scienceshengityselimetBENEFITSmedicinekeuhkosairaudetEXPOSUREkeuhkotSwimmingAsthmabusiness.industryINDUCED BRONCHOCONSTRICTIONResearchuimarit030229 sport sciencesAirway obstructionasthmahengitystietmedicine.diseaseallergyAsthmalääkkeetPOOL ATTENDANCE030228 respiratory systemswimming halls3121 General medicine internal medicine and other clinical medicineuintiSports medicinePhysical therapylääkehoitobusinessBMC Sports Science, Medicine and Rehabilitation
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Detection of fluorine using laser-induced breakdown spectroscopy and Raman spectroscopy

2017

In general, the detection of F and other halogens is challenging through conventional techniques. In this paper, various approaches for the qualitative and quantitative analysis of F using the laser-induced breakdown spectroscopy (LIBS) technique were demonstrated. In LIBS, fluorine detection can be realized by means of atomic lines and molecular bands. For the purposes of our experiment, two sets of pellets with various contents of CaF2, CaCO3 and cellulose were analyzed using a lab-based LIBS system under a He atmosphere. The fluorine atomic line at 685.60 nm was correlated with CaF signals proving their close relationship. Consequently, the limits of detection were determined for both an…

Analytical chemistrychemistry.chemical_element02 engineering and technology01 natural sciencesAnalytical ChemistryCrystalsymbols.namesakefluorineLaser-induced breakdown spectroscopySpectroscopySpectroscopyDetection limitChemistry010401 analytical chemistryta1182021001 nanoscience & nanotechnologyfluori0104 chemical scienceslaser-induced breakdown spectroscopyHalogenRaman spectroscopysymbolsFluorine0210 nano-technologyRaman spectroscopyQuantitative analysis (chemistry)
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Metabolic impact of adult-onset, isolated, growth hormone deficiency (AOiGHD) due to destruction of pituitary somatotropes.

2011

Growth hormone (GH) inhibits fat accumulation and promotes protein accretion, therefore the fall in GH observed with weight gain and normal aging may contribute to metabolic dysfunction. To directly test this hypothesis a novel mouse model of adult onset-isolated GH deficiency (AOiGHD) was generated by cross breeding rat GH promoter-driven Cre recombinase mice (Cre) with inducible diphtheria toxin receptor mice (iDTR) and treating adult Cre(+/-), iDTR(+/-) offspring with DT to selectively destroy the somatotrope population of the anterior pituitary gland, leading to a reduction in circulating GH and IGF-I levels. DT-treated Cre(-/-), iDTR(+/-) mice were used as GH-intact controls. AOiGHD im…

Anatomy and PhysiologyMousemedicine.medical_treatmentgh deficiencyMiceEndocrinology0302 clinical medicinefactor-iInsulinglucoseAge of OnsetInsulin-Like Growth Factor I2. Zero hunger0303 health scienceseducation.field_of_studyMultidisciplinarypancreatic beta-cellQRAnimal ModelsGHreceptor genehypothalamic expressionmedicine.anatomical_structureCarbohydrate MetabolismIntercellular Signaling Peptides and ProteinsMedicineincreased insulin sensitivityResearch ArticleHeparin-binding EGF-like Growth Factormedicine.medical_specialtymicediet-induced obesityDisfunción metabólicaSomatotropic cellSciencePopulationEndocrine System030209 endocrinology & metabolismBiologyCarbohydrate metabolismGrowth hormone deficiency03 medical and health sciencesModel OrganismsInsulin resistanceAnterior pituitaryreplacement therapyPituitary Gland AnteriorGrowth FactorsInternal medicinemedicineAnimalsObesityeducationBiologyNutrition030304 developmental biologyDiabetic EndocrinologyEndocrine PhysiologyInsulinDiabetes Mellitus Type 2Metabolyc disfunctionmedicine.diseaseHormonesMice Mutant StrainsSomatotrophsProlactinDietRatsDisease Models AnimalEndocrinologyPituitaryGrowth HormoneInsulin ResistanceEnergy IntakeEnergy MetabolismGHDPLoS ONE
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